Publications

Lourenco ARita, Ban Y, Crowley MJ, Lee SB, Ramchandani D, Du W, Elemento O, George JT, Jolly MKumar, Levine H et al..  2020.  Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis.. Cancer Res. 80(2):163-169.

Yomtoubian S, Lee SB, Verma A, Izzo F, Markowitz G, Choi H, Cerchietti L, Vahdat L, Brown KA, Andreopoulou E et al..  2020.  Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.. Cell Rep. 30(3):755-770.e6.

Williams ED, Gao D, Redfern A, Thompson EW.  2019.  Controversies around epithelial-mesenchymal plasticity in cancer metastasis.. Nat Rev Cancer. 19(12):716-732.

Altorki NK, Markowitz GJ, Gao D, Port JL, Saxena A, Stiles B, McGraw T, Mittal V.  2019.  The lung microenvironment: an important regulator of tumour growth and metastasis.. Nat Rev Cancer. 19(1):9-31.

Markowitz GJ, Havel LS, Crowley MJp, Ban Y, Lee SB, Thalappillil JS, Narula N, Bhinder B, Elemento O, Wong STc et al..  2018.  Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival.. JCI Insight. 3(13)

Gao D, Mittal V, Ban Y, Lourenco ARita, Yomtoubian S, Lee S.  2018.  Metastatic tumor cells - genotypes and phenotypes.. Front Biol (Beijing). 13(4):277-286.

Fischer KR, Altorki NK, Mittal V, Gao D.  2017.  Fischer et al. reply.. Nature. 547(7661):E5-E6.

Stawowczyk M, Wellenstein MD, Lee SB, Yomtoubian S, Durrans A, Choi H, Narula N, Altorki NK, Gao D, Mittal V.  2017.  Matrix Metalloproteinase 14 promotes lung cancer by cleavage of Heparin-Binding EGF-like Growth Factor.. Neoplasia. 19(2):55-64.

Zhao Z, Zhu X, Cui K, Mancuso J, Federley R, Fischer K, Teng G, Mittal V, Gao D, Zhao H et al..  2016.  In Vivo Visualization and Characterization of Epithelial-Mesenchymal Transition in Breast Tumors.. Cancer Res. 76(8):2094-2104.

Fischer KR, Durrans A, Lee S, Sheng J, Li F, Wong STC, Choi H, Rayes TEl, Ryu S, Troeger J et al..  2015.  Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.. Nature. 527(7579):472-6.

Durrans A, Gao D, Gupta R, Fischer KR, Choi H, Rayes TEl, Ryu S, Nasar A, Spinelli CF, Andrews W et al..  2015.  Identification of Reprogrammed Myeloid Cell Transcriptomes in NSCLC.. PLoS One. 10(6):e0129123.

Rayes TEl, Catena R, Lee S, Stawowczyk M, Joshi N, Fischbach C, Powell CA, Dannenberg AJ, Altorki NK, Gao D et al..  2015.  Lung inflammation promotes metastasis through neutrophil protease-mediated degradation of Tsp-1.. Proc Natl Acad Sci U S A. 112(52):16000-5.

Choi H, Sheng J, Gao D, Li F, Durrans A, Ryu S, Lee SB, Narula N, Rafii S, Elemento O et al..  2015.  Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model.. Cell Rep. 10(7):1187-201.

Catena R, Bhattacharya N, Rayes TEl, Wang S, Choi H, Gao D, Ryu S, Joshi N, Bielenberg D, Lee SB et al..  2013.  Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1.. Cancer Discov. 3(5):578-89.

Plummer PN, Freeman R, Taft RJ, Vider J, Sax M, Umer BA, Gao D, Johns C, Mattick JS, Wilton SD et al..  2013.  MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells.. Cancer Res. 73(1):341-52.

Ryu S, McDonnell K, Choi H, Gao D, Hahn M, Joshi N, Park S-M, Catena R, Do Y, Brazin J et al..  2013.  Suppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migration.. Cancer Cell. 23(1):63-76.

Gao D, Vahdat LT, Wong S, Chang JC, Mittal V.  2012.  Microenvironmental regulation of epithelial-mesenchymal transitions in cancer.. Cancer Res. 72(19):4883-9.

Gao D, Joshi N, Choi H, Ryu S, Hahn M, Catena R, Sadik H, Argani P, Wagner P, Vahdat LT et al..  2012.  Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition.. Cancer Res. 72(6):1384-94.

Gao D, Mittal V.  2012.  Tumor microenvironment regulates epithelial-mesenchymal transitions in metastasis.. Expert Rev Anticancer Ther. 12(7):857-9.

Ryu S, Joshi N, McDonnell K, Woo J, Choi H, Gao D, McCombie WR, Mittal V.  2011.  Discovery of novel human breast cancer microRNAs from deep sequencing data by analysis of pri-microRNA secondary structures.. PLoS One. 6(2):e16403.

Penack O, Henke E, Suh D, King CG, Smith OM, Na I-K, Holland AM, Ghosh A, Lu SX, Jenq RR et al..  2010.  Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth.. J Natl Cancer Inst. 102(12):894-908.

Yao Z, Fenoglio S, Gao DCheng, Camiolo M, Stiles B, Lindsted T, Schlederer M, Johns C, Altorki N, Mittal V et al..  2010.  TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer.. Proc Natl Acad Sci U S A. 107(35):15535-40.

Mellick AS, Plummer PN, Nolan DJ, Gao D, Bambino K, Hahn M, Catena R, Turner V, McDonnell K, Benezra R et al..  2010.  Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth.. Cancer Res. 70(18):7273-82.

Gao D, Nolan D, McDonnell K, Vahdat L, Benezra R, Altorki N, Mittal V.  2009.  Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression.. Biochim Biophys Acta. 1796(1):33-40.

Gao D, Mittal V.  2009.  The role of bone-marrow-derived cells in tumor growth, metastasis initiation and progression.. Trends Mol Med. 15(8):333-43.