October 12, 2021
In the new study, Mittal and co-senior authors Dr. Nasser Altorki, chief of the Division of Thoracic Surgery at Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center, and Dr. Dingcheng Gao, associate professor of cell and developmental biology at Weill Cornell Medicine, teamed up to determine how radiation has this immune-enhancing effect.
Using a mouse model of non-small-cell lung carcinoma, the most common form of lung cancer, they first established that this effect peaked at a moderate dose of radiation, and caused the quadrupling, to 40%, of the proportion of ICI-treated mice who survived tumor-free to the end of the two-month observation period. Click here to read the full article.